Scientist I, Biologics Drug Substance Development, Cell Culture Development job opportunity at AbbVie.



Date2026-05-01T00:03:14.558Z bot
AbbVie Scientist I, Biologics Drug Substance Development, Cell Culture Development
Experience: General
Pattern: Full-time
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Biologics Drug Substance Development, Cell Culture Development

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degreeMaster's (M.A.)
loacation San Francisco, California, United States Of America
loacation San Francisco,..........United States Of America
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Job DescriptionThe Cell Culture Development Group in South San Francisco, CA is seeking a Scientist I to join a talented and collaborative team to develop cell culture processes for GMP applications.In this position, you will perform cell culture process development, scale-up, and technology transfer activities in a well-supported and dynamic environment to help advance novel biotherapeutics into human clinical studies. KEY RESPONSIBILITIES: Perform inoculum expansion and cell bank generationExecute cell culture experiments using Ambr250 and 2L bioreactorsPerform pilot scale material generation using 50L, 200L and 500L single use bioreactorsExecute small scale and pilot scale depth filtration and centrifugation primary recovery processesPerform tech transfer of Master cell bank generation, cell culture and primary recovery processes to the GMP manufacturing facilitiesProvide person-in-plant support at the GMP manufacturing facilityPerform cell culture experiments to optimize N-1 perfusion processes as well as intensified fed-batch processesRepresent the cell culture development group for pipeline projects in cross-functional meetings and collaborate closely with cell line, purification, analytical and formulation development leads to meet project timelinesAuthor and review technical reports, GMP campaign summary reports, and relevant sections in regulatory filingsProactively identify and implement opportunities to optimize platform processes and deepen process understandingPresent scientific findings at internal or external conferencesCollaborate effectively with colleagues to promote a positive and efficient laboratory environment, and actively contribute ideas to enhance lab workflows and practices

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