Senior Scientist II, Analytical Development job opportunity at AbbVie.



Date2026-04-30T23:56:49.777Z bot
AbbVie Senior Scientist II, Analytical Development
Experience: General
Pattern: Full-time
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Analytical Development

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degreeGeneral
loacation San Diego, California, United States Of America
loacation San Diego, Cal..........United States Of America
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Job DescriptionWe seek a Senior Scientist II, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for guiding the biophysical analytical strategy and developing novel analytical methods for characterizing AbbVie’s mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on developing novel biophysical methods for characterizing mRNA, lipids, and plasmids. Working collaboratively across discovery research, this position will develop novel characterization methods to support process/product understanding, expansion of the mRNA/tLNP platform and pipeline, and build structure-activity relationships.  Responsibilities & Duties:Develop novel biophysical methods to characterize mRNA drug substance, including but not limited to LC, CE, LC-MS, MALLS, mass photometry, and plate-based assaysImprove plasmid characterization and build relationships to mRNA qualitySupport product characterization for tLNP platform/formulation development and lead candidate selectionLead mass-spec characterization of oligonucleotides, proteins, and lipidsSupport characterization of lipid content and related impuritiesSupport implementation of automation/high throughput (HTP) workflows and in-process analytical methods for routine and non-routine testingRepresent functional area in cross-functional pipeline and technology development teamsSupport method transfer and qualifications as neededDraft technical reports and documents as needed

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